Attachment structures :
Hématologie Cellulaire et Immunophénotypage des hémopathies
CHU de Lyon-HCL
UMR 1052-CNRS 5286, INSERM/CRCL-Anticorps Anticancer
Faculté de Médecine Rockefeller, Lyon
Adress :
Centre de Biologie et d’Anatomie Pathologique Lyon Sud
Laboratoire d’hématologie, CHU-Lyon Sud
165, Chemin du Grand Revoyet
69495 Pierre – Bénite Cedex-Lyon, France
Team website : None
CONECT-AML project leader in this team :
- Adriana PLESA, PH, team leader
- Research Gate: Adriana Plesa
Other project participants in the team :
- Carine HALFON-DOMENECH, PH
- Sebastien VIEL, MCU-PH
- Thierry WALZER, PhD
- Marine VILLARD, Research engineer
- Morgane DENIS, Research engineer
- Clarisse HOERNER, Research engineer
- Manon ZALA, Research engineer
- Delphine MANZONI, PH
- Pierre SUJOBERT, MCU-PH
- Charles DUMONTET, PU-PH
- Joris GUTRIN,Project manager
- Octavia CADASSOU, PhD
Summary of the project :
We are studying both the expression of ligands to NK receptors on the leukemic stem cell compartment CD34 + CD38- (LSC) and the expression of receptors on NK cells in order to identify new immunotherapeutic targets targeting this LSC-NK synapse. Our objective will be to propose new markers having a prognostic and theranostic role in AML in children, in addition to the molecular and cytogenetic markers already validated.
